Coding

Part:BBa_K2082206:Design

Designed by: Pascal Schmidt   Group: iGEM16_Bielefeld-CeBiTec   (2016-10-07)


Fusion protein SH2:AAA:cI(434)


Assembly Compatibility:
  • 10
    COMPATIBLE WITH RFC[10]
  • 12
    COMPATIBLE WITH RFC[12]
  • 21
    COMPATIBLE WITH RFC[21]
  • 23
    COMPATIBLE WITH RFC[23]
  • 25
    COMPATIBLE WITH RFC[25]
  • 1000
    COMPATIBLE WITH RFC[1000]


Design Notes

Badran et al. (2016) and Wojcik et al. (2010) were the main inspiration sources for creating this part.


Source

Gene synthesis of IDT for the creation of the SH2:cI(434) protein.

References

  • Badran, A. H., Guzov, V. M. & Huai, Q. et al. (2016) Continuous evolution of Bacillus thuringiensis toxins overcomes insect resistance. Nature 533 (7601), 58–63.
  • Wojcik, J., Hantschel, O. & Grebien, F. et al. (2010) A potent and highly specific FN3 monobody inhibitor of the Abl SH2 domain. Nature structural & molecular biology 17 (4), 519–527.